图书简介
The volume reports lectures and discussions presented at the International Congress on Glaucoma, held in Rome on 2-4 February, 1996. The Congress has been designed to clarify and possibly to define the fundamental steps for managing glaucoma patients. ’Decision making in therapy’ does not mean that the conference sessions have been devoted to therapeutic problems only, even if semeiologic and diagnostic problems are pertinent when aimed at successful therapy. Actually, it is necessary to distinguish the onset of glaucoma from ocular hypertension, to decide if and how to start treatment and the methods to assess its effectiveness, to understand if the failure of medical therapy justifies surgery and, above all, if intraocular pressure is, in any case, the most important risk factor to treat. Particular relevance has been given to normal-pressure glaucoma, whose physiopatho logical and clinical characteristics are still highly controversial. Two round tables were devoted to the recent advances in the treatment of glaucoma, which aims at lowering intraocular pressure, directly improving the eye trophism and regenerating the areas damaged by the disease. All ophthalmologists, particularly the younger ones, have had the opportunity to capi talize on the experience and knowledge of distinguished experts from different parts of the world. This has been an invaluable and perhaps unique opportunity for all of us to express our doubts and to enhance our scientific background.
Physiopathology.- Anatomic-Functional Aspects of Aqueous Humor Inflow.- Intraocular Pressure as a Risk Factor in Glaucoma.- Early Optic Disc Glaucomatous Damage.- Discussion.- Microvasculature of the Optic Disc and Glaucoma.- The Vascular Factors in Glaucoma.- Ocular Blood Flow and Its Autoregulation.- Discussion.- Diagnosis.- Imaging Optic Nerve and Nerve Fiber Layer: Optical Coherence Tomography.- Morphological Aspects in the Diagnosis and Pathogenesis of Glaucomatous Optic Neuropathy.- Sensivity and Specificity of Diagnostic Parameters of Glaucoma.- Early Visual Field Defects in Glaucoma: A Study of Eyes Developing Field Loss.- Clinical and Computerized Evaluation of the Retinal Nerve Fiber Layer.- Use of Provoked-Response Tests in Glaucoma: An Update.- Discussion.- Medical Therapy.- Diagnosing and Redefining Glaucoma.- When to Start Ocular Hypotensive Therapy?.- Lowering of Intraocular Pressure in the Treatment of Glaucoma.- The Adverse Effects of Topical Anti-Glaucoma Drugs.- The Role of Visual Field Examination During Treatment of Glaucoma.- Discussion.- Agonist Adrenergic Drugs.- Prostaglandins in the Treatment of Increased Intraocular Pressure.- Development of a Topically Active Carbonic Anhydrase Inhibitor.- Recovery of Glaucomatous Damage Following Treatment of Glaucoma.- Discussion.- Up-Dating on Hypotensive and Non Hypotensive Glaucoma Therapy.- Dopaminergic Drugs and Ocular Pressure.- Concomitant Ocular Effects of Hypotensive Antiglaucomatous Drugs.- Role of Carrier Substances in Hypotensive Drug Activity.- The Effect of Topical ?-Blockers on Plasma Lipids and Lipoproteins.- The Effect of Anti-Glaucoma Medication on Ocular Blood Flow.- Ocular Vasospasm and Calcium Channel Blockers in Glaucoma.- Discussion.- Normal Tension Glaucoma.- Pathogenetic Problems and Classification of Low Critical Tension Glaucoma.- Aspects of Normal Pressure Glaucoma.- Therapeutic Problems of Normal Tension Glaucoma.- Discussion.- Surgical Treatment.- Contact Transscleral Cyclophotocoagulation in the Treatment of Refractory Glaucoma.- A Controversial Decision: When to Operate on Chronic Glaucoma.- Antifibrosis Drugs in Filtration Surgery.- Trabeculectomy Utilizing Releasable Sutures, Combined with Phacoemulsification and Intraocular Lens Implantation: Efficacy and Safety.- Surgical Treatment of Hydrodynamic Changes Following Vitrectomy.- Discussion.- Valves and Drainage Implants.- Re-intervention as a Treatment of Glaucoma.- Outcomes of Surgical Treatment for Primary Open-Angle Glaucoma.- Discussion.- Up-Dating on Hypotensive and Non Hypotensive Glaucoma Therapy.- Blood Flow: a Target for Ocular Therapy in Glaucoma?.- The Ca2+ Channel Blocking Action of ?-Blockers in Bovine Retinal Microartery.- Antioxidant Drugs and Glaucoma.- Clinical Experience with Brimonidine Tartrate, an ?-2 Agonist.- Avenues Toward Neuroprotection of the Optic Nerve in Glaucoma.- Discussion.
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