Role of Capsaicin in Oxidative Stress and Cancer

辣椒素在氧化应激与癌症中的作用

肿瘤学

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1105
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884.00
优惠
平台大促 低至8折优惠
作      者
出  版 社
出版时间
2013年05月15日
装      帧
精装
ISBN
9789400763166
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页      码
178
语      种
英语
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图书简介
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
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