Checkpoint Responses in Cancer Therapy
肿瘤学Extensive research has uncovered a set of molecular surveillance mechanisms commonly called checkpoints which tightly monitor cell-cycle processes. Today 's anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now promises to uncover a new generation of anticancer drugs with improved therapeutic indices based on their ability to target emerging checkpoint components. Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, iden