Signaling Pathways in Cancer Pathogenesis and Therapy

癌症发病机理和治疗的信号转导途径

肿瘤学

原   价:
1105
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884.00
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平台大促 低至8折优惠
作      者
出  版 社
出版时间
2011年11月15日
装      帧
精装
ISBN
9781461412151
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页      码
156
语      种
英语
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图书简介
In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.
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