图书简介
We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic significance, their role in cancer was proposed and hotly debated. The critical early discoveries, even those made as recently as 25 years ago, were met with rejection; not skepticism or cautious restraint, but outright rejection. During the 60’s, there was a gradual acceptance of the association between viruses and cancer, the result of landmark studies in experimental systems, and this led to a frenzy of activity in the field. There followed another period of doubt and uncertainty, due to the difficulty in attempting to apply directly, and in retrospect inappropriately, the tenets of infectious disease to human cancers, only to have the field resurrected, revitalized and redirected by the explosion of progress in molecular biology and genetics.
Molecular Genetics of the RNA Tumor Viruses.- 1. Myc, a Genetic Element that is Shared by a Cellular Gene (proto-myc) and by Viruses with One (MC29) or Two (MH2) onc Genes.- 2. Viral and Cellular fos Gene.- 3. P21 ras Transforming Protein: Significance of the Carboxy Terminus.- 4. Protein Phosphorylation of Tyrosine in Normal and Transformed Cells.- 5. Activation of a Gene Coding for a Normal Human Growth Factor to One with Transforming Properties.- 6. Cell Cycle Control of c-myc Expression.- Endogenous Retrovirus Sequences in Human Cells.- 7. A New Class of Human Endogenous Retroviral Genes.- 8. Structure and Function of Human Endogenous Type C Retroviral DNAS.- 9. ERV3, A Full-Length Human Endogenous Provirus: Sequence Analysis and Evolutionary Relationships.- Molecular Biology of Human Cancers.- 10. Molecular Basis of Human B Cell Neoplasia.- 11. Stage Specific Transforming Genes in Lymphoid Neoplasms.- 12. Oncogenes Involved in Chronic Myelocytic Leukemia.- 13. Monoclonal Antibodies Generated to a Synthetic Peptide Define ras Gene Expression at the Single Cell Level in Human Colon and Mammary Carcinomas.- 14. Which Cancers are Caused by Activated proto-onc Genes?.- HTLV/LAV, T-Cell Leukemia and AIDS.- 15. The Family of Human T-Cell Leukemia Viruses and Their Role in the Cause of T-Cell Leukemia and AIDS.- 16. A Novel Human Lymphotropic Retrovirus (LAV): New Data on its Biology and Role in AIDS.- 17. Biology of Human T Cell Leukemia Viruses in Immunosuppression and AIDS.- 18. Human Retrovirus in Acquired Immunodeficiency Syndrome (AIDS).- 19. Human RNA and DNA Oncogenic Viruses and Their Importance in Transmissible and Malignant Diseases.- 20. Human T-Cell Leukemia Virus (HTLV) Antibodies in Mycosis Fungoides and Leukemias and Lymphomas.- 21. Immunologic Functions and the Pathogenesis of the Acquired Immune Deficiency Syndrome (AIDS).- Experimental Model Systems for the Study of Human Neoplasia and Related Diseases.- 22. Experimental Studies of the Pathogenesis of Feline Leukemia Virus Infection.- 23. Feline Leukemia and Sarcoma Viruses.- 24. Bovine Leukemia Virus: Past, Present and Future.- 25. A New Messenger RNA Expressed by Bovine Leukemia Virus Infected Cells.- 26. Primate Retroviruses and AIDS.- 27. Molecular Comparisons of the D-Type Retroviruses.- 28. Woodchuck Hepatitis Virus and Hepatitis B Virus as Related to Known RNA and DNA Tumor Viruses and Hepatocellular Carcinoma.- 29. Establishment of Virus-Negative Cell Lines Derived from Radiation- or Chemically-Induced T-Cell Lymphomas in NFS/N Mice, and Generation of Oncogenic Virus from These Cell Lines Following Infection of A Non-Oncogenic Ecotropic Virus.- Perspectives.- 30. Perspectives and Prospects of Molecular Biology in the Control of Human Malignancies.- 31. Implications for the Control of Human Cancer.
Trade Policy 买家须知
- 关于产品:
- ● 正版保障:本网站隶属于中国国际图书贸易集团公司,确保所有图书都是100%正版。
- ● 环保纸张:进口图书大多使用的都是环保轻型张,颜色偏黄,重量比较轻。
- ● 毛边版:即书翻页的地方,故意做成了参差不齐的样子,一般为精装版,更具收藏价值。
关于退换货:
- 由于预订产品的特殊性,采购订单正式发订后,买方不得无故取消全部或部分产品的订购。
- 由于进口图书的特殊性,发生以下情况的,请直接拒收货物,由快递返回:
- ● 外包装破损/发错货/少发货/图书外观破损/图书配件不全(例如:光盘等)
并请在工作日通过电话400-008-1110联系我们。
- 签收后,如发生以下情况,请在签收后的5个工作日内联系客服办理退换货:
- ● 缺页/错页/错印/脱线
关于发货时间:
- 一般情况下:
- ●【现货】 下单后48小时内由北京(库房)发出快递。
- ●【预订】【预售】下单后国外发货,到货时间预计5-8周左右,店铺默认中通快递,如需顺丰快递邮费到付。
- ● 需要开具发票的客户,发货时间可能在上述基础上再延后1-2个工作日(紧急发票需求,请联系010-68433105/3213);
- ● 如遇其他特殊原因,对发货时间有影响的,我们会第一时间在网站公告,敬请留意。
关于到货时间:
- 由于进口图书入境入库后,都是委托第三方快递发货,所以我们只能保证在规定时间内发出,但无法为您保证确切的到货时间。
- ● 主要城市一般2-4天
- ● 偏远地区一般4-7天
关于接听咨询电话的时间:
- 010-68433105/3213正常接听咨询电话的时间为:周一至周五上午8:30~下午5:00,周六、日及法定节假日休息,将无法接听来电,敬请谅解。
- 其它时间您也可以通过邮件联系我们:customer@readgo.cn,工作日会优先处理。
关于快递:
- ● 已付款订单:主要由中通、宅急送负责派送,订单进度查询请拨打010-68433105/3213。
本书暂无推荐
本书暂无推荐