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Preface; Part I. Basic Sciences: 1. Pathology of cavernous malformations Sachin Batra, Barbara Crain, Rachel Engelmann, Joaquin Camara-Quintana and Daniele Rigamonti; 2. Epidemiology and natural history of cavernous malformations Rachel Engelmann, Sachin Batra, Angela Li, Joaquin Camara-Quintana and Daniele Rigamonti; 3. Familial cavernous malformations: a historical survey Leslie Morrison; 4. Clinical and molecular genetics of cerebral cavernous malformations Xavier Ayrignac and Elisabeth Tournier-Lasserve; 5. Molecular biology of cerebral cavernous malformation Jun Zhang; 6. Cavernous malformations and radiation Eugenio Pozzati and Nicola Acciarri; 7. Neuroimaging of cavernous malformations Doris D. M. Lin and Wael Abdalla; 8. Clinical features and medical management of cavernous malformations Michel J. Berg and Tegan Vay; Part II. Clinical Features, Imaging and Diagnostic Work-up: 9. Hemorrhage: new and recurrent Colin B. Josephson and Rustam Al-Shahi Salman; 10. Medical management of seizures and the presurgical evaluation of medically intractable epilepsy Gregory K. Bergey; Part III. Therapy: 11. The pros and cons of conservative and surgical treatment of cavernous malformations Pablo F. Recinos, Sheng-Fu Larry Lo, Christopher Wallace and Daniele Rigamonti; 12. Surgical treatment of cavernous malformations associated with epilepsy Mahua Dey and Issam Awad; 13. Surgery of spinal cavernous malformations M. Yashar S. Kalani and Robert F. Spetzler; 14. Surgical treatment of cavernous malformations in children Edward R. Smith and R. Michael Scott; 15. Resection of cavernous malformations of the brainstem Helmut Bertalanffy, Jan-Karl Burkhardt, Ralf Alfons Kockro, Johannes Sarnthein and Oliver Bozinov; 16. Principles for managing cavernous malformations in eloquent locations Uğur Türe and Ahmet Hilmi Kaya; 17. Radiosurgery of cavernous malformations: the Pittsburgh experience Douglas Kondziolka, L. Dade Lunsford, Hideyuki Kano and John C. Flickinger; Part IV. Basic Aspects: 18. Genetic counselling Leslie Morrison; 19. Special problems in cavernous malformations Richard Leigh and Robert J. Wityk; Index.

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