图书简介
Membrane emulsification is a novel technique and its application in bioengineering and biomedical area is promising. This book summarizes the principle, preparation and bio-applications by utilizing uniform particle size, also introduces recent new development in preparation and applications in the release of protein/peptide, anticancer and vaccine are included, as well as in protein separation. More importantly, it also includes the direct, rapid, and rotary membrane emulsification equipment. It will be of particular interest to chemists, chemical engineers and materials scientists to advance the technique to produce new, novel materials with controlled characteristics, and also to students and researchers in biomedical science and bioengineering fields.
Chapter 1: Membrane emulsification process: principle and model Chapter 2: Preparation of hydrophobic microspheres from O/W emulsion 2.1 Preparation from monomer system 2.2 Preparation from preformed polymer system 2.3 Morphology control of microsphere Chapter 3: Preparation of hydrophilic microspheres from W/O emulsion 2.1 Membrane modification and hydrophobic membrane preparation 2.2 Preparation from monomer system 2.3 Preparation from preformed polymer system 2.4 Morphology control of microsphere Chapter 4: Preparation of microcapsule from W/O/W emulsion 2.1 Preparation of microcapsule 2.2 Preparation of composite microsphere 2.3 Preparation of super-porous microsphere Chapter 5: Rapid membrane emulsification process for small particle preparation 5.1 Preparation of hydrophobic microspheres from O/W emulsion 5.2 Preparation of hydrophilic microspheres from W/O emulsion 5.3 Preparation of microcapsule from double emulsion Chapter 6: Applications of uniform particles in sustained release of protein/peptide drugs 6.1 PLA, PLGA, PELA 6.1.1 Strategy to improve encapsulation efficiency 6.1.2 Strategy to maintain bioactivity of drugs 6.2 Polysaccharide 6.2.1 Strategy to improve encapsulation efficiency 6.2.2 Strategy to maintain bioactivity of drugs Chapter 7: Applications of uniform particles in targeting delivery of anticancer drugs 7.1 Size and morphology effects 7.2 Strategy for particle design to improve drug efficacy Chapter 8: Applications of uniform particles in vaccine delivery personized therapeutic vaccine 8.1 Effect of physico-chemical properties of particles on immune-response 8.2 Strategy for particle design to enhance the immunity 8.3 Biomimetic particles for vaccine delivery Chapter 9: Applications of uniform particles in protein separation 9.1 Uniform agarose microsphere for protein separation 9.2 Super-porous microsphere for vaccine separation Chapter 10: Membrane emulsification equipment 10.1 Direct membrane emulsification equipment 10.2 Rapid membrane emulsification equipment 10.3 Rotary membrane emulsification equipment Chapter 11: Summary and Prospect
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