图书简介
This book presents a review of a rapidly developing field of viral nanotechnology in the context of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Viral nanotechnology is founded on the unexpected properties of viral nanoparticles. It emphasizes applications of viral nanotechnology to improving health and adva
Preface. Editors. Contributors. Introduction. Introduction to Capsid Architecture. Self-Assembling Virus-like and Virus-Unlike Particles. Electron Cryomicroscopy and Image Reconstruction of Viral Nanoparticles. X-Ray Analysis of Viral Nanoparticles. Computational Methods for Engineering Protein 3D Nanoobjects. Viral Nanoparticles: Principles of Construction and Characterization. Immunology of Virus-like Particles. Nanomedicine: General Considerations and Examples. Virus-like Particles: A Versatile Tool for Basic and Applied Research on Emerging and Reemerging Viruses. Virus-like Particles Derived from Hepatitis Viruses. History and Potential of Hepatitis B Virus Core as a VLP Vaccine Platform. SplitCore: Advanced Nanoparticulate Molecular Presentation Platform Based on the Hepatitis B Virus Capsid. Use of VLPs in the Design of Malaria Vaccines. Use of HBcAg as an Adjuvant in DNA-Based Vaccines: An Unexpected Journey. Bacteriophage Virus-like Particles as a Platform for Vaccine Discovery. Production of Virus-like Particles in Plants. Bionanomaterials from Plant Viruses. Assembly of Bluetongue Virus-like Particle: Multiprotein Complex and Its Use as Vaccine. Virus-like Particles Based on Polyomaviruses and Human Papillomaviruses as Vectors for Vaccines, Preventive and Therapeutic Immunotherapy, and Gene Delivery. Applications of Viral Nanoparticles Based on Polyomavirus and Papillomavirus Structures. Nanoparticles of Norovirus. Virus-like Particle Enzyme Encapsulation: Confined Catalysts and Metabolic Materials. Principles of Design of Virus Nanoparticles for Imaging Application. Enveloped Viruses with Single-Stranded Negative RNA Genome as Objects and Subjects of VLP Nanotechnology. Traditional and Novel Trends in Influenza Vaccines. Retrovirus-Derived Virus-like Particles. Cancer Therapy Applying Viral Nanoparticles. Alphaviral Vectors for Cancer Treatment. Synthetic Virus-like Particles in Vaccine Design. Index.
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