图书简介
Human Placental Trophoblasts: Impact of Maternal Nutrition explores the vital roles of trophoblasts play in fetal growth and pregnancy, giving you new insight into the modulation of placental trophoblast functions by nutrients. It also reviews the role of fatty acids, folic acids, and specific vitamins in this aspect. The book highlights the critical role of nutrients on human placental development and its’ in utero programming effects on the development of chronic diseases such as type 2 diabetes, cardiovascular diseases, hypertension, and obesity in later life.The book begins with discussions of the central process of placentation and its regulation on size and growth of the fetus. It also covers the effects of key macronutrients on placental growth, metabolism, transport, and secretory function. The text details important vitamins and few micronutrients and their roles in the feto-placental growth and development. It includes information on the influence of maternal lifestyle and environmental factors on regulation of the growth, metabolism and gene expression in the feto-placental unit. A review of the genes linked to the process of placentation rounds out the coverage.An examination of a broad range of evidence in the areas of placental growth, function, and its impact on feto-placental outcome, the book presents new knowledge on nutrition and its relevance with early human development. This includes not only the effects of maternal nutrients on possible neonatal growth and development but also their regulation by maternal lifestyle associated factors. A fine blending of epidemiology, clinical nutrition, perinatal and neonatal medicine, and biochemistry and molecular biology areas of research activities, the book helps you to understand the impact of maternal nutrition on placentation and its relevance with pregnancy outcome and fetal programming of adult health and disease.
EARLY PLACENTATION: REGULATION OF TROPHOBLAST GROWTH AND DEVELOPMENT Human Placenta Development, Structure, and Organization in Relation to Function and Fetal Development T. Henriksen, A.M. Holme, H. Horne, M.B. Holm, and T.M. Michelsen Molecular Regulation of Human Extravillous Trophoblast Development JUErgen Pollheimer and Martin Knoefler Epigenetics and the Placenta: Impact of Maternal Nutrition Leslie Myatt and Kohzoh Mitsuya Maternal Diet, Trophoblast Biology, and Epigenetic Regulation Daniel Vaiman MATERNAL NUTRITION AND FETAL GROWTH AND DEVELOPMENT Prepregancy Nutrition and Pregnancy Outcome Christine Henriksen Placental Amino Acid Transport in Response to Maternal Nutrition during Pregnancy Allison L.B. Shapiro and Theresa L. Powell Fatty Acid Uptake and Metabolism in the Human Placenta Asim K. Duttaroy The Roles of Fatty Acids in Fetal Development Emilio Herrera and Henar Ortega-Senovilla Role of Maternal Long-Chain Polyunsaturated Fatty Acids in Placental Development and Function Alka Rani, Akshaya Meher, Nisha Wadhwani, and Sadhana Joshi Importance of Cholesterol and Cholesterol Transporters in the Placental Trophoblast during Pregnancy Arjun Jain and Christiane Albrecht Maternal Fatty Acids and Their Effects on Placentation Sanjay Basak and Asim K. Duttaroy VITAMINS AND MINERALS: EFFECT ON PLACENTATION Maternal Micronutrients, Placental Growth, and Fetal Outcome Irene Cetin, Chiara Mando, and Manuela Cardellicchio Folic Acid Uptake and Its Regulation in the Placenta E. Keating, J.R. Araujo, and F. Martel Vitamin D Effects on Pregnancy and Trophoblast Function: Limited Data yet Endless Possibilities Bryanne Colvin, Mark S. Longtine, and D. Michael Nelson Choline and Placental Trophoblast Development Sze Ting (Cecilia) Kwan, Julia H. King, and Marie A. Caudill Role of Calcium in Fetal Development Evemie Dube and Julie Lafond REGULATION OF TROPHOBLAST ANGIOGENESIS AND INVASION Maternal Obesity and Placental Vascular Function Louiza Belkacemi, Michael G. Ross, and Mina Desai Placental Dysfunction and Future Maternal Cardiovascular Disease Anne Cathrine Staff and Christopher W.G. Redman Trophoblast-Uterine Natural Killer Cell Interactions and Their Effect on Cytokines and Angiogenic Growth Factors Gendie E. Lash and Judith N. Bulmer Hyperglycemia on Trophoblast Invasion and Angiogenesis Sanjay Basak and Asim K. Duttaroy Role of Cytokines in Healthy and Pathological Pregnancies Abhilash D. Pandya, Mrinal K. Das, and Johannes Rolin ENVIRONMENTAL AND LIFESTYLE FACTORS IN PREGNANCY The Aryl Hydrocarbon Receptor in the Human Placental Trophoblast: The Impact of Nutraceuticals and Naturals Products Petr Pavek and Tomas Smutny Impact of Environmental Pollutants on Placentation Nur Duale, Kristine Bjerve Gutzkow, Tim Hofer, and Birgitte Lindeman EPIGENETICS, MICRORNA, AND PLACENTAL GENE EXPRESSION Differential Gene Expression of the Placenta in Normal and Pathological Human Pregnancy Vasilis Sitras and Ganesh Acharya Placental Gene Expression in Pathological Pregnancies Saumitra Chakravarty Regulation of microRNA Expression and Function of First-Trimester and Term Placentas in Humans Yuping Wang
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