图书简介
This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC.Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.
I Basics.- 1 Anatomy and pathology of the peritoneum.- 2 Pharmacovigilance of topical chemotherapy in the peritoneum.- II Diagnostics and natural course.- 3 Imaging diagnostics of tumors of the peritoneum.- 4 Role of laparoscopy in the diagnosis of tumors of the peritoneum.- 5 Scoring systems for CRS and HIPEC.- 6 Natural course of peritoneal carcinomatosis.- III Therapy options of systemic therapy.- 7 Inductive preoperative chemotherapy for peritoneal metastases of tumors of the upper GI tract.- 8 Inductive preoperative chemotherapy for peritoneal metastases of tumors of the lower GI tract including appendiceal carcinoma.- IV Treatment options for surgical cytoreduction.- 9 Procedures of parietal and visceral peritonectomy in the upper abdomen.- 10 Technique of visceral and parietal peritonectomy in the lower abdomen.- 11 Procedures of parietal and visceral peritonectomy interenterically.- 12 Cytoreduction - preparation devices.- V therapy options of intraperitoneal therapy and experimental approaches.- 13 Application of IPC, HIPEC and PIPAC.- 14 Cytokine-induced senescence: an experimental therapy for peritoneal tumors.- 15 Mechanism of action and experimental and clinical data on regional hyperthermia.- 16 HIPEC in childhood.- VI Potentially curative approach.- 17 Importance of intraperitoneal chemotherapy as a prophylaxis after curative resection of a gastrointestinal carcinoma.- 18 Indication of CRS and HIPEC in Pseudomyxoma peritonei.- 19 Significance of CRS and HIPEC in mesothelioma.- 20 Indication of CRS and HIPEC in peritoneal metastatic gastric carcinoma.- 21 Indication of CRS and HIPEC in peritoneal metastases of colorectal carcinomas.- 22 Indication of CRS and HIPEC in peritoneal metastases of ovarian cancer.- 23 Indication of CRS and HIPEC in peritoneal metastases of NET and small intestinal carcinomas.- 24 Indication of CRS and HIPEC in peritoneal metastases of pancreatic carcinomas.- 25 Indications of CRS and HIPEC in Incidentally Detected Peritoneal Carcinomatosis.- VII VII Palliative treatment attempt of advanced peritoneal metastasis.- 26 Importance of systemic chemotherapy in advanced peritoneal metastasis.- 27 Importance of PIPAC in advanced peritoneal metastasis.- VIII Complications in the Palliative Chemotherapy of Peritoneal Cancer.- 28 Complications in the Palliative Chemotherapy of Peritoneal Cancer.- 29 Cytoreductive surgery for complications of peritoneal carcinomatosis.- 30 IPEC, HIPEC, Bidirectional Chemotherapy and Immunotherapy in Aggressive Peritoneal Metastasis.- IX Perioperative treatment and prophylaxis of treatment related complications.- 31 Preoperative Management: Risk Assessment, Conditioning, Nutritional Aspects, Special Preparation, Including Bowel.- 32 Safety Considerations for Intraoperative Use of Cytostatic Agents.- 33 Preventing Complications of Cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy.- 34 Nutritional Concepts in Patients with Peritoneal Tumors.- 35 Perioperative management.- X Quality of life.- 36 Quality of life at CRS and HIPEC.- 37 PIPAC Therapy and Quality of Life.- XI Recurrent diesease.- 38 Follow-Up to Prevent Recurrence of Peritoneal Malignancies.- 39 Localization of Localization of Peritoneal Tumor Recurrence.- 40 Treatment Options for Peritoneal Tumor Recurrence.- XII Environmental Aspects.- 41 Importance of Psycho-Oncology for Tumors of the Peritoneum.- 42 Nursing Aspects of Peritoneal Surface Malignancy.- XIII Guidelines and centres.- 43 Guideline preparation and center development for the treatment of peritoneal tumors in Germany.- 44 Guideline preparation and center development for the treatment of peritoneal tumors in Switzerland.- Service part.- 45 Checklists for the treatment of tumors of the peritoneum. Framework SOP.- Index.
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