Redox Regulation of Differentiation and De-differentiation（Oxidative Stress and Disease）
分化与去分化的氧化还原调节
生物化学
￥
2053.00
售 价：
￥
1642.00
优惠
平台大促 低至8折优惠
发货周期：预计5-7周发货
出 版 社
出版时间
2021年10月14日
装 帧
精装
页 码
392
开 本
254 x 178 mm (7 x 10)
语 种
英文
综合评分
5 分
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图书简介
Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine.
Key Features
Provides the first summary on this important topic
Reviews redox-dependent development of model organisms and single organs
Highlights the redox-regulated pathways important for differentiation processes
Illustrates the potential of redox medicine
Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration
Written by leading experts in the field
Related Titles
Ayyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-
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