图书简介
This volume provides a comprehensive understanding of the enigmatic identity of the glycome, a complex but important area of research that has been;largely ignored due to;its complexity. The authors thoroughly deal with almost all aspects of the glycome, i.e., elucidation of the glycan identity enigma and its role in regulation of the cellular process, and in disease etiology.;The book;bridges the knowledge gap in understanding the glycome, from being a cell signature to its applications in disease etiology. In addition, it details many of the major insights regarding the possible role of the glycome in various diseases as a therapeutic marker.The book systematically covers the major aspects of the glycome, including the significance of substituting the diverse monosaccharide units to glycoproteins, the role of glycans in disease pathologies, and the challenges and advances in glycobiology. The authors stress the significance and huge encoding power of carbohydrates as well as provide helpful insights in framing the bigger picture.The Glycome: Understanding the Diversity and Complexity of Glycobiology details state-of-the-art developments and emerging challenges of glycome biology, which are going to be key areas of future research, not only in the glycobiology field but also in pharmaceutics.
1. Trends and Advancements in Glycobiology: Towards Development of Glycan-Based Therapeutics Yaser Rafiq Mir and Raja Amir H. Kuchay 2. Defects in the Human Glycome: Congenital and Non-Congenital Disorders Mumtaz Anwar 3. Glycome in Immunological Processes: Current Scenario and Future Prospects Zeba Mueed, Manali Singh, Abhay Mishra, and Nitesh Kumar Poddar 4. Role of Glycans in Neurodegeneration Abhai Kumar and Smita Singh 5. Glycome in Metastasis: Glycan Remodeling and Tumor Progression Ayyagari Archana, Durgashree Dutta, Safikur Rahman, and Rinki Minakshi 6. Glycans in the Host-Pathogen Interaction Muzafar Jan and Sunil K. Arora 7. Glycome in Microbial Infections and Immune Evasion Abid Qureshi 8. Acylation as a Vital Post-Glycosylation Modification of Proteins: Insights and Therapeutics Prospects Usma Manzoor, Snowber Shabir Wani, Fasil Ali, Parvaiz A. Dar, and Tanveer Ali Dar 9. Glycome Profiling in Plants: Towards Understanding the Scenario of Carbohydrates Reetika Mahajan, Muslima Nazir, Jahangir A. Dar, Shazia Mukhtar, Muntazir Mushtaq, Susheel Sharma, Jasdeep Chatrath Padaria, Shafiq A. Wani, and Sajad Majeed Zargar 10. Sugars: Coping the Stress in Plants Ritika Rajpoot
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