Fc Mediated Activity of Antibodies:Structural and Functional Diversity(Current Topics in Microbiology and Immunology)

Fc介导的抗体活性:结构与功能多样性

肿瘤学

售   价:
1840.00
发货周期:外国库房发货,通常付款后3-5周到货
出  版 社
出版时间
2019年09月19日
装      帧
精装
ISBN
9783030310523
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页      码
150
开      本
9.21 x 6.14 x 0.44
语      种
英文
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库存 64 本
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图书简介
This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
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