Asymmetric Synthesis of 3, 3-Disubstituted Oxindoles

3,3-二取代氧化吲哚的不对称合成

有机化学

原   价:
1390.00
售   价:
1042.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2019年09月13日
装      帧
精装
ISBN
9781786347299
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页      码
300
语      种
英文
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库存 30 本
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图书简介
Indole derivatives are the most common heterocycle compounds present in nature, for this reason, they have been referred to as "privileged structures". In fact, many approved drugs — and natural products — belong to this family. Among indole derivatives, oxindoles have a structural complexity, which have stimulated generations of synthetic chemists to design strategies for assembling these structures, and their enantioselective synthesis is still growing. This book proposes to describe the known enantioselective syntheses of oxindole derivatives. It is divided in six chapters each referring to a specific class of asymmetric oxindole derivatives. After the introduction, Chapter 2 describes all-carbon spirooxindoles; Chapter 3, open-chain 3, 3-dialkyloxindoles; Chapter 4, 3-substituted-3-aminooxindoles; Chapter 5, 3-substituted-3-hydroxyoxindoles; Chapter 6, 3-hetero-3-substituted oxindoles. It will be a useful tool for synthetic chemists, who assemble total synthesis of natural products, as well as for drug discovery chemists either in academic or in industry R&S laboratories.
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