2-Methoxyestradiol Effectiveness on Glial and Neuronal Cells

药理学

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作      者
出版时间
2011年03月27日
装      帧
平装
ISBN
9783844320251
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页      码
128
开      本
9.00 x 6.00 x 0.30
语      种
英文
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图书简介
2-Methoxyestradiol (2ME), a metabolite deriving from 17- estradiol, is a well-established antiangiogenic, apoptotic and antiproliferative agent in cell cultures and animal models. 2ME may also exert its cytotoxic activity by interacting with tubulin and by causing an impairment of the microtubular system. In this study was investigated the relative effectiveness of 2ME on glial and neural cell cultures in inducing morpho-functional changes and alteration of the microtubular system physiology. Results demonstrate that 2ME is more e
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