Human Dna Polymerases:Biology, Medicine And Biotechnology

人类DNA聚合酶:生物学,医学和生物技术

生物数学

原   价:
1720.00
售   价:
1290.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2017年11月13日
装      帧
精装
ISBN
9789813226401
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页      码
400
语      种
英文
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库存 30 本
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图书简介
Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes. Key Features: o The only book to merge basic science, biotechnological applications and marketing opportunities of DNA polymerases o The most extensive literature coverage of the field, with more than 1,000 cited references and updated with the most recent contributions received by scientists all over the world o Written by four leading experts in DNA polymerases, it gives the most complete overview of the field from its historical origins to the latest developments
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