图书简介
A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy
Chapter 1. Background Emine Ekici Chapter 2. Introduction to Vaccination Nezih Piskinpasa and OEmer Faruk Karasakal Chapter 3. Fundamentals of Modern Peptide Synthesis Korkut Ulucan and Muhsin Konuk Chapter 4. Peptide Synthesis and Characterization Stages Mustafa Kemal Gumus Chapter 5. Conjugation of Polymers with Biomolecules and Polymeric Vaccine Development Technologies S. Arda Ozturkcan Chapter 6. What are Polymeric Carriers? Gulderen Karakus and Dolunay Sakar Dasdan Chapter 7. Conjugation and Other Methods in Polymeric Vaccines OEzgur OEzay Chapter 8. Polymeric Nanoparticle Preparation Methods Mithat Celebi Chapter 9. Peptides in Brain Disorders Huseyin UEnubol and Goekben Hizli Sayar Chapter 10. Pseudo-proteins and related synthetic amino acid based polymers promising for constructing artificial vaccines Ramaz Katsarava Chapter 11. Peptide Vaccines in Cancer Diseases OEzge OEznur OEzcan, Rumeysa Rabia Kocaturk, Fadime Canbolat Chapter 12. Antioxidant Peptides Rumeysa Rabia Kocaturk, Fatmanur Zehra Zelka, OEzge OEznur OEzcan, Fadime Canbolat Chapter 13. Peptide Vaccine Joel Lim Whye Ern, Tan Shen Leng, Tee Yi Na and Palaniarajan Vijayaraj Kumar Chapter 14. Adjuvants Of Vaccine in Immunotoxicology Fadime Canbolat Chapter 15. Role of Epigenetics in Immunity and Immune Response to Vaccination Ozan Tiryakioglu Chapter 16. \"Omics\" technologies in vaccine research Sezer Okay Chapter 17. Computer-Aided Epitope Identification and Design of Epitope Mimetics. Greg Czyryca
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