Preface Acknowledgments About the author Chapter 1 Introduction 1.1 Why a book with monographs on topical drugs? 1.2 Data provided in this book Chapter 2 An overview of allergic contact dermatitis from topical drugs 2.1 Side effects of topical drugs 2.2 Allergic contact dermatitis from topical drugs 2.2.1 Prevalence 2.2.2 Predisposing factors 2.2.3 Clinical manifestations 2.2.4 The allergens 2.3 Diagnostic procedures 2.4 Uses of corticosteroids 2.5 Allergic contact dermatitis from corticosteroids 2.6 The corticosteroid sensitizers 2.7 Diagnostic procedures in suspected corticosteroid allergy 2.8 Cross-reactivity between corticosteroids Chapter 3 Monographs of topical drugs that have caused contact allergy/allergic contact dermatitis 3.1 Introduction 3.2 Aceclidine 3.3 Aceclofenac 3.4 Acetarsone 3.5 Acetazolamide 3.6 Acetylcysteine 3.7 Acexamic acid 3.8 Acyclovir 3.9 Adapalene 3.10 Alcaftadine 3.11 Alclometasone dipropionate 3.12 Aluminum acetate 3.13 Ambroxol 3.14 Amcinonide 3.15 Aminocaproic acid 3.16 Aminolevulinic acid 3.17 3-(Aminomethyl)pyridyl salicylate 3.18 Amlexanox 3.19 Amorolfine 3.20 Amylocaine 3.21 Antazoline 3.22 Anthrarobin 3.23 Apraclonidine 3.24 Arbekacin 3.25 Atropine 3.26 Azidamfenicol 3.27 Azithromycin 3.28 Bacitracin 3.29 Beclomethasone dipropionate 3.30 Befunolol 3.31 Belladonna extract 3.32 Bendazac 3.33 Benzarone 3.34 Benzocaine 3.35 Benzoyl peroxide 3.36 Benzydamine 3.37 Betamethasone 3.38 Betamethasone dipropionate 3.39 Betamethasone sodium phosphate 3.40 Betamethasone valerate 3.41 Betaxolol 3.42 Bibrocathol 3.43 Bifonazole 3.44 Bimatoprost 3.45 Bismuth subnitrate 3.46 Bismuth tribromophenate 3.47 Brimonidine 3.48 Bromelains 3.49 Budesonide 3.50 Bufexamac 3.51 Buprenorphine 3.52 Butamben 3.53 Caine mix III 3.54 Calcipotriol 3.55 Canrenone 3.56 Carbarsone 3.57 Carmustine 3.58 Carteolol 3.59 Chloral hydrate 3.60 Chloramphenicol 3.61 Chlordantoin 3.62 Chlorphenesin 3.63 Chlorpheniramine 3.64 Chlorphenoxamine 3.65 Chlorproethazine 3.66 Chlorquinaldol 3.67 Chlortetracycline 3.68 Ciclesonide 3.69 Ciclopirox olamine 3.70 Clemizole 3.71 Clindamycin 3.72 Clioquinol 3.73 Clobetasol propionate 3.74 Clobetasone butyrate 3.75 Clocortolone pivalate 3.76 Clonidine 3.77 Cloprednol 3.78 Clotrimazole 3.79 Cloxyquin 3.80 Coal tar 3.81 Colistimethate 3.82 Colistin 3.83 Collagenase clostridium histolyticum 3.84 Cortisone acetate 3.85 Croconazole 3.86 Cromoglicic acid 3.87 Crotamiton 3.88 Cyclobenzaprine 3.89 Cyclopentolate 3.90 Cyproheptadine 3.91 Desonide 3.92 Desoximetasone 3.93 Dexamethasone 3.94 Dexamethasone acetate 3.95 Dexamethasone phosphate 3.96 Dexamethasone sodium phosphate 3.97 Dexchlorpheniramine 3.98 Dexketoprofen 3.99 Dibekacin 3.100 Dibrompropamidine 3.101 Dibucaine 3.102 Diclofenac 3.103 Diethylstilbestrol 3.104 Diflorasone diacetate 3.105 Diflucortolone valerate 3.106 Difluprednate 3.107 4,5-Dihydro-1H-imidazole monohydrochloride 3.108 Diltiazem 3.109 Dimethindene 3.110 Dioxopromethazine 3.111 Diperodon 3.112 Diphenhydramine 3.113 Dipivefrin 3.114 Dithranol 3.115 Dorzolamide 3.116 Doxepin 3.117 Dyclonine 3.118 Echothiophate 3.119 Econazole 3.120 Efinaconazole 3.121 Enilconazole 3.122 Enoxolone 3.123 Ephedrine 3.124 Epinephrine 3.125 Erythromycin 3.126 Estradiol 3.127 Estradiol benzoate 3.128 Estrogens, conjugated 3.129 Ethacridine 3.130 Etisazole 3.131 Etofenamate 3.132 Eucaine 3.133 Felbinac 3.134 Fenoterol 3.135 Fenticonazole 3.136 Fepradinol 3.137 Feprazone 3.138 Fluclorolone acetonide 3.139 Fludrocortisone acetate 3.140 Flufenamic acid 3.141 Flumethasone pivalate 3.142 Flunisolide 3.143 Fluocinolone acetonide 3.144 Fluocinonide 3.145 Fluocortolone 3.146 Fluocortolone caproate 3.147 Fluocortolone pivalate 3.148 Fluorometholone 3.149 Fluorouracil 3.150 Fluprednidene acetate 3.151 Fluprednisolone 3.152 Flurandrenolide 3.153 Flurbiprofen 3.154 Fluticasone propionate 3.155 Framycetin 3.156 Furaltadone 3.157 Fusidic acid 3.158 Gentamicin 3.159 Glycol salicylate 3.160 Gramicidin 3.161 Halcinonide 3.162 Halometasone 3.163 Haloprogin 3.164 Halquinol 3.165 Hexamidine 3.166 Hexamidine diisethionate 3.167 Hirudoid (R) cream 3.168 Homatropine 3.169 Hydrocortisone 3.170 Hydrocortisone aceponate 3.171 Hydrocortisone acetate 3.172 Hydrocortisone butyrate 3.173 Hydrocortisone hemisuccinate 3.174 Hydrocortisone probutate 3.175 Hydrocortisone valerate 3.176 Hydroquinone 3.177 Ibacitabine 3.178 Ibuprofen piconol 3.179 Ibuproxam 3.180 Ichthammol 3.181 Idoxuridine 3.182 Indomethacin 3.183 Interferons 3.184 Iodine 3.185 Iodoform 3.186 Iodoquinol 3.187 Iothion 3.188 Isoconazole 3.189 Isoflupredone acetate 3.190 Isothipendyl 3.191 Kanamycin 3.192 Ketoconazole 3.193 Ketoprofen 3.194 Ketorolac tromethamine 3.195 Ketotifen 3.196 Lactic acid 3.197 Lanoconazole 3.198 Latanoprost 3.199 Levobunolol 3.200 Levocabastine 3.201 Lidocaine 3.202 Lincomycin 3.203 Luliconazole 3.204 Mabuprofen 3.205 Mafenide 3.206 Mazipredone 3.207 Mechlorethamine 3.208 Medrysone 3.209 Mephenesin 3.210 Meprylcaine 3.211 Mesulfen 3.212 Methoxsalen 3.213 Methyl aminolevulinate 3.214 Methyldiphenhydramine 3.215 Methyl nicotinate 3.216 Methylphenidate 3.217 Methylprednisolone 3.218 Methylprednisolone aceponate 3.219 Methylprednisolone acetate 3.220 Methylprednisolone hemisuccinate 3.221 Methyl salicylate 3.222 Methyl salicylate 2-ethylbutyrate 3.223 Metipranolol 3.224 Metoprolol 3.225 Metronidazole 3.226 Miconazole 3.227 Minoxidil 3.228 Miscellaneous topical drugs 3.229 Mitomycin C 3.230 Mometasone furoate 3.231 Monobenzone 3.232 Mupirocin 3.233 Naftifine 3.234 Naphazoline 3.235 Neomycin 3.236 Neticonazole 3.237 Nicoboxil 3.238 Nicotine 3.239 Nifuratel 3.240 Nifuroxime 3.241 Nifurprazine 3.242 Nitrofurazone 3.243 Nitroglycerin 3.244 Nonoxynol-9 3.245 Norethisterone 3.246 Nylidrin 3.247 Nystatin 3.248 Olaflur 3.249 Oxiconazole 3.250 Oxybuprocaine 3.251 Oxyphenbutazone 3.252 Oxyquinoline 3.253 Oxytetracycline 3.254 Paromomycin 3.255 Pecilocin 3.256 Penicillamine 3.257 Penicillins, unspecified 3.258 Pheniramine 3.259 Phenylbutazone 3.260 Phenylephrine 3.261 Piketoprofen 3.262 Pilocarpine 3.263 Pimecrolimus 3.264 Piperazine 3.265 Pirenoxine 3.266 Piroxicam 3.267 Piroxicam cinnamate 3.268 Polidocanol 3.269 Polymyxin B 3.270 Povidone-iodine 3.271 Pramoxine 3.272 Prednicarbate 3.273 Prednisolone 3.274 Prednisolone acetate 3.275 Prednisolone caproate 3.276 Prednisolone hemisuccinate 3.277 Prednisolone pivalate 3.278 Prednisolone sodium metazoate 3.279 Prednisolone valerate acetate 3.280 Prednisone 3.281 Prilocaine 3.282 Procaine 3.283 Procinonide 3.284 Proflavine 3.285 Promestriene 3.286 Promethazine 3.287 Propanocaine 3.288 Propantheline 3.289 Proparacaine 3.290 Propipocaine 3.291 Propranolol 3.292 Pyrazinobutanone 3.293 Pyridoxine 3.294 Pyrilamine 3.295 Pyrithione zinc 3.296 Pyrrolnitrin 3.297 Quinoline mix 3.298 Resorcinol 3.299 Retapamulin 3.300 Retinol 3.301 Retinyl palmitate 3.302 Rifamycin 3.303 Ripasudil 3.304 Rotigotine 3.305 Rubidium iodide 3.306 Salicylamide 3.307 Salicylic acid 3.308 Scopolamine 3.309 Selenium sulfide 3.310 Sertaconazole 3.311 Silver nitrate 3.312 Sirolimus 3.313 Sisomicin 3.314 Sodium fluoride 3.315 Spaglumic acid 3.316 Spironolactone 3.317 Stannous fluoride 3.318 Stepronin 3.319 Sulbentine 3.320 Sulconazole 3.321 Sulfacetamide 3.322 Sulfadiazine silver 3.323 Sulfanilamide 3.324 Sulfiram 3.325 Suprofen 3.326 Tacalcitol 3.327 Tacrolimus 3.328 Terconazole 3.329 Testosterone 3.330 Tetracaine 3.331 Tetrachlorodecaoxide 3.332 Tetracycline 3.333 Tetrahydrozoline 3.334 Thiabendazole 3.335 Thiamine 3.336 Thiocolchicoside 3.337 Thioctic acid 3.338 Timolol 3.339 Tioconazole 3.340 Tiopronin 3.341 Tioxolone 3.342 Tixocortol pivalate 3.343 Tobramycin 3.344 Tocopherol 3.345 Tocopheryl acetate 3.346 Tolazoline 3.347 Tolciclate 3.348 Tolnaftate 3.349 Travoprost 3.350 Tretinoin 3.351 Triafur 3.352 Triamcinolone 3.353 Triamcinolone acetonide 3.354 Triamcinolone diacetate 3.355 Triamcinolone hexacetonide 3.356 Tribenoside 3.357 Triethanolamine polypeptide oleate condensate 3.358 Trifluridine 3.359 Trimebutine 3.360 Tripelennamine 3.361 Tromantadine 3.362 Tromethamine 3.363 Tropicamide 3.364 Troxerutin 3.365 Tyrothricin 3.366 Undecylenic acid 3.367 Vancomycin 3.368 Virginiamycin 3.369 Xantocillin Chapter 4 Allergic contact dermatitis to ingredients other than the active drug 4.1 Introduction 4.2 Case series 4.3 Non-drug ingredients that have caused contact allergy/allergic contact dermatitis by their presence in topical pharmaceuticals Chapter 5 Immediate contact reactions (contact urticaria) Chapter 6 Systemic drugs and delayed-type hypersensitivity: A preview 6.1 Systemic drugs and delayed-type hypersensitivity reactions 6.2 Systemic drugs to be discussed in the next volume of ’Monographs in contact allergy’ Index

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