图书简介
Discover the fundamentals and intricacies of a subject at the interface of chemistry and biology with this authoritative resource Chemistry and Biology of Non-canonical Nucleic Acids delivers a comprehensive treatment of the chemistry and biology of non-canonical nucleic acids, including their history, structures, stabilities, properties, and functions. You’ll learn about the role of these vital compounds in transcription, translation, regulation, telomeres, helicases, cancers, neurodegenerative diseases, therapeutic applications, nanotechnology, and more. An ideal resource for graduate students, researchers in physical, organic, analytical, and inorganic chemistry will learn about uncommon nucleic acids, become the common non-canonical nucleic acids that fascinate and engage academics and professionals in private industry. Split into 15 chapters covering a wide range of aspects of non-canonical nucleic acids, the book explains why these compounds exist at the forefront of a new research revolution at the intersection of chemistry and biology. Chemistry and Biology of Non-canonical Nucleic Acids also covers a broad range of topics critical to understanding these versatile and omnipresent chemicals, including: A discussion of the dynamic regulation of biosystems by nucleic acids with non-canonical structures The role played by nucleic acid structures in neurodegenerative diseases and various cancers An exploration of the future outlook for the chemistry and biology of non-canonical nucleic acids An introduction to the history of canonical and non-canonical structures of nucleic acids An analysis of the physicochemical properties of non-canonical nucleic acids Perfect for biochemists, materials scientists, and bioengineers, Chemistry and Biology of Non-canonical Nucleic Acids will also earn a place in the libraries of medicinal and pharmaceutical chemists who wish to improve their understanding of life processes and the role that non-canonical nucleic acids play in them.
Dedication Foreword Series editor’s preface Preface brief table of contents Table of Contents (ToC) list of plates/figures/maps list of tables Notes on Contributors (LoC) Acknowledgments (personal) Acknowledgments (list of sources) List of abbreviations Glossary Nomenclature/Notation Timeline/Chronology Maps History for Canonical and Noncanonical Structures of Nucleic Acids Structures of Nucleic Acids Now Stability of Noncanonical Nucleic Acids Physicochemical Properties of Noncanonical Nucleic Acids Telomere Transcription Translation Replication Helicase Dynamic Regulation of Biosystems by Nucleic Acids with Noncanomical Structures Cancer and Nucleic Acids Structures Neurodegenerative Diseases and Nucleic Acids Structures Therapeutic Applications Material Science and Nanotechnology of Nucleic Acids Future outlook for chemistry and biology of noncanonical nucleic acids Appendix Glossary Nomenclature/Notation Notes References Bibliography Credits and Sources/Acknowledgements Table of Cases Index
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