Design of Caspase Inhibitors as Potential Clinical Agents

Caspase抑制剂用做潜在临床药剂的设计

医学生物化学

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658.00
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平台大促 低至8折优惠
发货周期:预计5-7周发货
出  版 社
出版时间
2019年08月30日
装      帧
平装
ISBN
9780367386573
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页      码
312
开      本
6-1/8 x 9-1/4
语      种
英文
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图书简介
Caspases (cysteine aspartyl proteases) represent one of the most specific protease families described to date. As caspase family members are involved in pro-inflammatory responses, inhibition of caspase activity represents a novel yet core approach to disease treatment. Design of Caspase Inhibitors as Potential Clinical Agents discusses the role of caspases in inducing cell death. It reviews recent efforts to develop small molecule inhibitors that are capable of modulating caspase activity. The text also examines the difficulties encountered in transitioning small molecule inhibitors from the lab to clinical use, and discusses how these challenges can best be overcome to allow continued progress.
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