图书简介
Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of genomics-driven advances across sports medicine, exercise physiology and nutrition, synthesizing key themes from these fields and highlighting opportunities to advance personalized medicine and athlete health management. In the book, international experts discuss possible therapeutic strategies and next steps in research, thus empowering physicians, fitness experts, genetic counselors and translational scientists to employ genomic data in improving patient fitness, interpreting genomic test results, and advancing new studies in exercise and nutrition genomics across diverse populations. Contributors address current knowledge of individualized exercise response in athletic performance, as well as the genetics of musculoskeletal exercise-related phenotypes, exercise-related injury, fat loss, and flexibility, and neurodegenerative and cardiovascular disorders in athletes. Finally, traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with direct-to-consumer genetic testing and ethical aspects of employing genomic data and pharmacogenomic aids in sports medicine and personalized nutrition.
PART I. SPORTS GENETICS 1. Introduction to genetics of sport and exercise 2. Genetic profile of elite endurance athletes 3. Genes and elite sprinters 4. Genes and elite strength athlete status 5. Genetics of team-sport performance 6. Variation of Mitochondrial DNA and elite athletic performance 7. Psychogenetics and sport 8. Ethical issues of genetic testing in sport and exercise PART II. EXERCISE GENETICS AND MOLECULAR PHYSIOLOGY 9. Genes and response to aerobic training 10. Genes and response to resistance training 11. Transcriptomic predictors of individual adaptation to exercise 12. Epigenetics in exercise science 13. Genes and individual responsiveness to exercise-induced fat loss PART III. GENETICS OF MUSCULOSKELETAL EXERCISE-RELATED PHENOTYPES 14. Genetics of muscle mass 15. Genetics of flexibility 16. Genetics of muscle fiber composition PART IV. GENETICS OF SPORT-RELATED DISEASES AND MEDICAL CONDITIONS 17. Genes, soft-tissue injuries and muscle cramp 18. Genetics of neurodegenerative disorders in athletes 19. Genetic variation and cardiovascular adaptation to exercise PART V. NUTRIGENETICS AND PHARMACOGENETICS IN SPORT AND EXERCISE 20. Perspectives of personalized weight loss interventions based on nutrigenetic, epigenetic, fitness genetics and metagenomic data in fitness and sport 21. The future of genetically-based personalized nutritional and pharmacological aids in sport
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