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Preface; 1. The medical and cultural history of testosterone and the testes Eberhard Nieschlag and Susan Nieschlag; 2. Testosterone: biosynthesis, transport, metabolism and (non-genomic) actions C. Marc Luetjens and Gerhard F. Weinbauer; 3. Pathophysiology of the androgen receptor Olaf Hiort, R. Werner and Michael Zitzmann; 4. Methodology for measuring testosterone, DHT and SHBG in a clinical setting Manuela Simoni, Flaminia Fanelli, Laura Roli and Uberto Pagotto; 5. The behavioral correlates of testosterone John Bancroft; 6. The role of testosterone in spermatogenesis Liza O’Donnell and Robert I. McLachlan; 7. Androgens and hair: a biological paradox with clinical consequences Valerie Anne Randall; 8. Testosterone and bone Dirk Vanderschueren, Mieke Sinnesael, E. Gielen, F. Claessens and S. Boonen; 9. Androgens effects on the skeletal muscle Shalender Bhasin, Ravi Jasuja, Carlo Serra, Rajan Singh, Thomas W. Storer, Wen Guo, Thomas G. Travison and Shezad Basaria; 10. Testosterone and cardiovascular disease Kevin S. Channer and T. Hugh Jones; 11. Testosterone, obesity, diabetes and the metabolic syndrome T. Hugh Jones and Kevin S. Channer; 12. Testosterone and erection Mario Maggi and Hermann M. Behre; 13. Testosterone and the prostate John T. Isaacs and Samuel R. Denmeade; 14. Clinical use of testosterone in hypogonadism and other conditions Eberhard Nieschlag and Hermann M. Behre; 15. Testosterone preparations for clinical use in males Hermann M. Behre and Eberhard Nieschlag; 16. Androgens in male senescence Jean-Marc Kaufman, Guy T’Sojen and Alex Verleulen; 17. Androgen therapy in non-gonadal disease David J. Handelsman; 18. Review of guidelines on diagnosis and treatment of testosterone deficiency Ronald S. Swerdloff and Christina C. L. Wang; 19. Pathophysiology of estrogen action in men Vincenzo Rochira, Daniele Santi and Cesare Carani; 20. Dehydroepiandrosterone (DHEA) and androstenedione Bruno Allolio, Wiebke Arlt and Stefanie Hahner; 21. The state-of-the-art in the development of selective androgen receptor modulators (SARMs) Ravi Jasuja, M. Zacharov and Shalender Bhasin; 22. The essential role of testosterone in hormonal male contraception Eberhard Nieschlag and Hermann M. Behre; 23. Testosterone use in women Susan R. Davis; 24. Detection of illegal use of androgens and SARMs Wilhelm Schänzer and Mario Thevis; 25. Clinical effects of doping with anabolic steroids Elena Vorona and Eberhard Nieschlag; Index.

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