图书简介
Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This review will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Key Features:
○ Uniquely places nutrition and epigenetics in a global health context or addresses the ethical and social implications of this new research
○ A contemporary review that explores the relationship between nutrition and epigenetics in the context of global health with consideration of the ethical issues that it raises, which have not really been articulated in detail in any review
Basic Mechanisms in Epigenetics (K A Lilllycrop); Nutrition, Epigenetics and the Early Life — Origins of Disease: Evidence from Human Studies (N D’Vaz & R-C Huang); The Early Life — Nutritional Environment, Epigenetics and Developmental Programming of Disease: Evidence from Animal Models (M H Vickers); Lipids and Epigenetics (G C Burdge); Circadian Biology: Its Interaction with Metabolism and Nutrition (J D Johnston); Nutrition, Epigenetics and Ageing (J C Mathers & H-M Byun); Nutrition and Epigenetics: Evidence for Multi- and Trans-Generational Effects (C S Rosenfeld); Epigenetic Biomarkers and Global Health (P Costello & M A Hanson); Nutrition, Epigenetics and Health: Evolutionary Perspectives (S English & T Uller); The Body Politic: Epigenetics and Society (N Davis)
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