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1 Oxygen: Boon yet Bane DS introducing oxygen toxicity and reactive species; 2 Redox chemistry: the essentials; 3 Antioxidant defences synthesized in vivo; 4 Antioxidants from the diet; 5 Oxidative stress and redox regulation: adaptation, damage, repair, senescence and death; 6 Measurement of reactive species; 7 Reactive species can pose special problems needing special solutions: some examples; 8 Reactive species can be useful: some more examples; 9 Reactive species can be poisonous: their role in toxicology; 10 Reactive species in disease: friends or foes?; 11 Ageing, nutrition, disease and therapy: a role for antioxidants?; Appendix

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