Transporters as Drug Targets(Methods and Principles in Medicinal Chemistry)

作为药物靶标的转运蛋白 第70卷

药物化学

售   价:
1516.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2017年01月04日
装      帧
精装
ISBN
9783527333844
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页      码
354
开      本
168.3x244.5mm
语      种
英文
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图书简介
After a general introduction on the importance of targeting transporter proteins with drugs, individual transporter classes are systematically introduced and their pharmacology and physiology explained. All transporter families with known or suspected importance as drug targets are covered here, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With a focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.
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