Assessing Quality of Life in Clinical Trials:Methods and practice

Assessing Quality of Life in Clinical Trials:Methods and practice

临床试验中对生命质量的评估：方法与实践
流行病学

售价：

发货周期：预计5-7周发货

作者

Fayers, Peter; Hays, Ron

出版社

Oxford University Press

出版时间

2005年03月10日

装帧

精装

ＩＳＢＮ

9780198527695

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页码

482

开本

240x168mm

语种

英文

版次

2nd ed.

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暂无评分

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Researchers in all clinical fields are fully aware of the importance of Quality of Life measurements in judging the efficacy of a given treatment. Psychological criteria play an important role in this evaluation. Assessing Quality of Life in Clinical Trials explores the current state of the art and illustrates the benefits and potential of health related quality of life assessment in clinical trials. It cover a wide range of analytical issues, emphasizing new and innovative approaches that are of practical and clinical importance. The book will have widespread appeal to clinical trialists and researchers from a wide range of specialties.

Preface; 1. Developing and evaluating questionnaires; 1.1: Ron Hays: Generic versus disease-targeted instruments; 1.2: Elaine McColl: Developing questionnaires; 1.3: Ron Hays & Dennis Revicki: Reliability and validity, including responsiveness; 1.4: Ron Hays & Peter Fayers: Evaluating multi-item scales; 1.5: Bryce Reeve & Peter Fayers: Rasch models & IRT; 2. Adapting and using questionnaires; 2.1: Patrick Marquis: Translating and evaluating questionnaires - cultural issues; 2.2: Jakob Bjorner & John Ware: CAT and item banking; 2.3: David Cella: Developing a questionnaire using IRT - a case study of fatigue; 2.4: Elaine McColl & Peter Fayers: Proxy assessments and context effects; 3. Analysis; 3.1: Diane Fairclough: Analysing longitudinal studies of QOL; 3.2: Dennis Revicki & Diane Fairclough: Preventing missing data; 3.3: Diane Fairclough: Analysing studies with missing data; 3.4: Mogens Groenvold & Morten Petersen: Differential item functioning (DIF) for analysing cultural differences; 3.5: Dennis Revicki: Reporting analyses from clinical trials; 4. Interpreting QoL in individuals and groups; 4.1: Ciaran O’Boyle, Stefan Höfer & Lena Ring: Individualised QoL; 4.2: David Osoba & Madeleine King: Meaningful differences; 4.3: David Osoba: Health-related QoL outcomes in clinical trials; 4.4: Carolyn Schwartz, Mirjam Sprangers & Peter Fayers: Response shift; 4.5: Galina Velikova & Penny Wright: Individual patient monitoring; 5. Measures for clinical trials; 5.1: Jakob Bjorner, Peter Fayers & Ellen Idler: Self-rated health; 5.2: Stephen Coons & Jim Shaw: Generic adult health status measures; 5.3: Jeanne Landgraf: Measurement of HRQL in child/adolescent clinical trials; 5.4: Barbara Vickrey: Developing disease-targeted measures for neurolgic conditions; 6. Beyond clinical trials; 6.1: Paul Kind: Values and valuation; 6.2: David Feeny: Preference-based measures; 6.3: Mandy Ryan & Karen Gerard: Discrete choice experiments; 6.4: Peter Fayers & Neil Scott: Combining clinical trials - meta analysis

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