The Blood-Brain Barrier and Drug Delivery to the CNS

药物化学

原   价:
2328.00
售   价:
1862.00
优惠
平台大促 低至8折优惠
发货周期:预计5-7周发货
出  版 社
出版时间
2000年05月16日
装      帧
精装
ISBN
9780824703943
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页      码
264
开      本
234x156 mm
语      种
英文
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图书简介
This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research.Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from nearly 40 international specialists in diverse fields, The Blood-Brain Barrier and Drug Delivery to the CNS assesses the properties of the blood-brain barrier to determine and measure drug permeability in animals and humans presents techniques to predict successful drug uptake through in vitro systems or by computation of physicochemical parameters examines the multidrug resistance protein P-glycoprotein as a natural transporter analyzes current drug designs to known requirements for transport looks at drug delivery systems for the brain and much more!Densely packed with over 800 literature references, drawings, photographs, x-rays, tables, and equations, The Blood-Brain Barrier and Drug Delivery to the CNS is a vital addition to the bookshelves of biochemists, pharmacists, clinical and research pharmacologists, neuroscientists and neurologists, and graduate and medical school students in these disciplines.
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