Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

结核分枝杆菌发病机制及其与宿主生物体的相互作用

医学微生物学

原   价:
1658.00
售   价:
1326.00
优惠
平台大促 低至8折优惠
出  版 社
出版时间
2013年12月15日
装      帧
精装
ISBN
9783642402319
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页      码
245
语      种
英语
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图书简介
Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms.In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.
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