Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications

钠钙交换:不断增长的病理生理学影响范围(会议录)

发育生物学,古生物学

原   价:
1768.00
售   价:
1326.00
优惠
平台大促 低至8折优惠
作      者
出  版 社
出版时间
2012年12月15日
装      帧
精装
ISBN
9781461447559
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页      码
487
语      种
英语
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库存 30 本
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图书简介
This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of ncx1 gene, the molecular identification of the mitochondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract.The book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mitochondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE.
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