图书简介

Part I. Epidemiology, Pathophysiology, and Pathogenesis of Fetal and Neonatal Brain Injury: 1. Neonatal encephalopathy: epidemiology and overview; 2. Neuronal cell death mechanisms relevant to humans: rethinking modeling neonatal hypoxic-ischemic encephalopathy; 3. Cellular and molecular biology of hypoxic-ischemic encephalopathy; 4. The pathogenesis of preterm brain injury; Part II. Pregnancy, Labor, and Delivery Complications Causing Brain Injury: 5. Prematurity and complications of labor and delivery; 6. Risks and complications of multiple gestation; 7. Intrauterine growth restriction; 8. Maternal diseases that affect fetal and neonatal neurodevelopment; 9. Obstetrical conditions and practices that affect the fetus and newborn; 10. Fetal and neonatal injury as a consequence of maternal substance abuse; 11. Hypertensive disorders of pregnancy; 12. Complications of labour and delivery; 13. Fetal responses to asphyxia; 14. Antepartum evaluation of fetal well-being; 15. Intrapartum evaluation of the fetus; Part III. Diagnosis of the Infant with Brain Injury: 16. Clinical manifestations of hypoxic-ischemic encephalopathy; 17. The use of EEG and aEEG in assessing the term and preterm brain; 18. Neuroimaging in the evaluation of pattern and timing of fetal and neonatal brain abnormalities; 19. Light-based assessment of the brain; 20. Placental pathology and the etiology of fetal and neonatal brain injury; 21. Timing perinatal hypoxic-ischemic brain injury; Part IV. Specific Conditions Associated with Fetal and Neonatal Brain Injury: 22. Congenital malformations of the brain; 23. Neurogenetic disorders of the brain; 24. Hemorrhagic lesions of the central nervous system; 25. Neonatal stroke; 26. Neurodevelopmental consequences of neonatal hypoglycemia; 27. Hyperbilirubinemia and kernicterus; 28. Polycythemia and fetal?maternal bleeding; 29. Hydrops fetalis; 30. Bacterial sepsis in the neonate; 31. Neonatal bacterial meningitis; 32. Neurological sequelae of congenital and perinatal infections; 33. Neurological complications of perinatal human immunodeficiency virus infection; 34. Inborn errors of metabolism and single gene disorders with features of neonatal encephalopathy; 35. Acidosis and alkalosis; 36. Persistent pulmonary hypertension of the newborn; 37. Pediatric cardiac surgery: relevance to fetal and neonatal brain injury; 38. Neonatal resuscitation: immediate management; 39. Improving performance, reducing error, and minimizing risk in the delivery room; 40. Extended management following resuscitation; 41. Endogenous and exogenous neuroprotective mechanisms after hypoxic-ischemic injury; 42. Neonatal seizures: evaluation, treatment, and prognosis; 43. Nutritional support of the asphyxiated infant; 44. Early outcomes after extremely preterm birth; 45. Cerebral palsy: advances in definition, classification, management and outcome; 46. Neurodevelopmental and neurobehavioral outcomes of prematurity: cognition, language, academic skills, and behavioral and emotional profiles; 47. Neurocognitive outcomes in term infants with neonatal encephalopathy; 48. Neonatal neuroethics; 49. Medicolegal issues in perinatal brain injury.

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