图书简介
This book focuses on the process of stress sensing and transducing mechanical force into biochemical signals. It helps define mechanomics, which describes the mechanical state of a biological system.
馆藏图书馆
Yale University Library
Princeton University Library
1. Introduction Roger D. Kamm and Mohammad R. K. Mofrad; 2. Endothelial mechanotransduction Peter F. Davies and Brian P. Helmke; 3. Role of the plasma membrane in endothelial cell mechanosensation of shear stress Peter J. Butler and Shu Chien; 4. Mechanotransduction by membrane mediated activation of G protein coupled receptors and G proteins Yan-Liang Zhang, John A. Frangos and Mirianas Chachisvilis; 5. Cellular mechanotransduction: interactions with the extracellular matrix Andrew D. Doyle and Kenneth M. Yamada; 6. Role of ion channels in cellular mechanotransduction: lessons from the vascular endothelium Abdul I. Barakat and Andrea Gojova; 7. Towards a modular analysis of cell mechano-sensing and transduction: an operations manual for cell mechanics Benjamin J. Dubin-Thaler and Michael P. Sheetz; 8. Tensegrity as a mechanism for integrating molecular and cellular mechanotransduction mechanisms Donald E. Ingber; 9. Nuclear mechanics and mechanotransduction Shinji Deguchi and Masaaki Sato; 10. Microtubule bending and breaking in cellular mechanotransduction Andrew D. Bicek, Dominique Seetapun, and David J. Odde; 11. A molecular perspective on mechanotransduction in focal adhesions Seung E. Lee, Roger D. Kamm and Mohammad R. K. Mofrad; 12. Protein conformational change: a molecular basis of mechanotransduction Gang Bao; 13. Translating mechanical force into discrete biochemical signal changes: multimodularity imposes unique properties to mechanotransductive proteins Vesa P. Hytönen, Michael L. Smith and Viola Vogel; 14. Mechanotransduction through local autocrine signaling Nikola Kojic and Daniel J. Tschumperlin; 15. The interaction between fluid-wall shear stress and solid circumferential strain affects endothelial cell mechanobiology John M. Tarbell; 16. Micro- and nanoscale force techniques for mechanotransduction Nathan J. Sniadecki, Wesley R. Legant and Christopher S. Chen; 17. Mechanical regulation of stem cells: implications in tissue remodeling Kyle Kurpinski, Randall R. R. Janairo, Shu Chien and Song Li; 18. Mechanotransduction: role of nuclear pore mechanics and nucleocytoplasmic transport Christopher B. Wolf and Mohammad R. K. Mofrad; 19. Summary and outlook Mohammad R. K. Mofrad and Roger D. Kamm.
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