图书简介

xix Preface; 1 Introductions to Basic Origins of Life Questions; 1.1 What Is Life?; 1.2 The RNA World Hypothesis; 1.3 Prebiotic Chemistry and Chemical Evolution; 1.4 Summary; 1.5 Exercises; 1.6 Suggested Reading; 2 Origin of Earth, Its Atmosphere, and Oceans: The First Molecules; 2.1 An Introduction to Geology; 2.2 Formation of Earth and its Geological History; 2.3 Earth’s First Atmospheres: From Strongly to Weakly Reducing Mixtures; 2.4 The First Organic Molecules: Exogenous Delivery, Endogenous Production, and Impact Synthesis; 2.5 Oceans and Submarine Hydrothermal Vents; 2.6 Land and Hydrothermal Fields; 2.7 Summary; 2.8 Exercises; 2.9 Suggested Reading; 3 An Overview of Biochemistry; 3.1 A Brief History of Life on Earth; 3.2 The Essential Features of Prokaryotes; 3.3 DNA, RNA, and Proteins; 3.4 Summary; 3.5 Exercises; 3.6 Suggested Reading; 4 An Overview of Metabolism and Reaction Networks; 4.1 Introduction to Metabolism; 4.2 The Chemoton Model and the Organization of Cellular Metabolism; 4.3 The Central Metabolic Pathways in Prokaryotes; 4.4 Other Important Biosynthetic Pathways; 4.5 Summary; 4.6 Exercises; 4.7 Suggested Reading; 5 Sugars, Nucleobases and RNA: Prebiotic Ribonucleotide Synthesis; 5.1 Sugar Nomenclature, Structure, and Stereochemistry; 5.2 RNA Nomenclature and Structure; 5.3 Prebiotic Sugar Synthesis; 5.4 Nucleobase Synthesis; 5.5 Ribonucleoside/tide Synthesis; 5.6 Summary; 5.7 Exercises; 5.8 Suggested Reading; 6 Aqueous Phase Amino Acid Chemistry; 6.1 Amino Acid Structure and Nomenclature; 6.2 Prebiotic Amino Acid Synthesis; 6.3 Miller-Urey-type Experiments; 6.4 Amino Acids in Meteorites; 6.5 Summary; 6.6 Exercises; 6.7 Suggested Reading; 7 Nonenzymatic Polymerization of Ribonucleic Acids and Peptides; 7.1 Nonenzymatic Polymerization Is Thought to be a Prerequisite for Life’s Emergence; 7.2 Polymerization with Condensing Agents; 7.3 Nonenzymatic Template-Directed Synthesis; 7.4 Summary; 7.5 Exercises; 7.6 Suggested Reading; 8 Protocells: Compartmentalization, Replication and Integrated Molecular Function; 8.1 Protocells and the Importance of Compartments; 8.2 Different Types of Protocell Compartments; 8.3 The Chemistry of Lipid Membrane Vesicles; 8.4 Prebiotic Fatty Acid and Phospholipid Synthesis; 8.5 Nonenzymatic Template-Directed RNA Synthesis within Vesicles; 8.6 An Introduction to Synthetic Biology; 8.7 Summary; 8.8 Exercises; 8.9 Suggested Reading

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