Opsin-free Optogenetics

图书简介

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating;the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools. Key Features Describes new developments in non-opsin-based optogenetic tools Introduces cutting-edge methods for precise modulation of cell signaling Highlights applications of optogenetic regulation of cellular functionsCovers contributions from an international team of leading expertsRelated TitlesLim, W.

Table of Content Chapter 1 Optogenetic dissection of a two-component calcium influx pathway Xiaoxuan Liu, Yingshan Wang, Yubin Zhou, and Guolin Ma* Chapter 2 High-throughput engineering of a light-activatable Ca2 channel Lian He*, Liuqing Wang, and Youjun Wang* Chapter 3 Optogenetic activation of TrkB signaling Peiyuan Huang, Zhihao Zhao, Lei Lei, and Liting Duan* Chapter 4 Spatiotemporal modulation of neural repair Huaxun Fan, Qin Wang, Kai Zhang*, and Yuanquan Song* Chapter 5 Optogenetic control of neural stem cell differentiation Yixun Su, Taida Huang, Kai Zhang, and Chenju Yi* Chapter 6 An optogenetic toolbox for remote control of programmed cell death Ningxia Zhang and Ji Jing* Chapter 7 Control of protein levels in Saccharomyces cerevisiae by optogenetic modules that act on protein synthesis and stability Sophia Hasenjäger, Jonathan Trauth, and Christof Taxis* Chapter 8 Optogenetics as a tool to study neurodegeneration and signal transduction Prabhat Tiwari* and Nicholas S. Tolwinski* Chapter 9 Opsin-free optogenetics: brain and beyond Jongryul Hong, Yeonji Jeong, and Won Do Heo* Chapter 10 Constructing a far-red light-induced split-Cre recombinase system for controllable genome engineering Meiyan Wang, Jiali Wu, and Haifeng Ye* Chapter 11 Tools and Technologies for Wireless and Non-invasive Optogenetics Guangfu Wu, Vagif Abdulla, Yiyuan Yang, Michael Schneider, and Yi Zhang*

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Opsin-free Optogenetics（Methods in Signal Transduction Series） 无视蛋白光遗传学：技术及其应用 遗传学

Opsin-free Optogenetics（Methods in Signal Transduction Series）

无视蛋白光遗传学：技术及其应用
遗传学