图书简介
This book equips deTal care providers wTh aThorough underTanding ofThe emergingTherapiesThT promiseTo revolTionizeThe clinical managemeT of periodoTal diseases. ExiTingTherapiesTargTedToThe oral microbiome alone oTen failTo provide favorable clinical oTcomes. Local inflammTion andTissue deTruTion may persiT and periodoTalTissue regenerTion is nT prediTably achieved. In recognTion ofThese shoTcomings, curreT research effoTs are focused on underTandingThe biological iTeraTions bTweenThe hoT andThe resideT microbiome and ideTifying key molecules and molecular pThwaysThT can be used for moreTargTed, individualizedTherapiesThT will reTrain oral inflammTion and reTore periodoTalTissue homeoTasis.This book iTroduces novel conceTs and moleculesThT are curreTly beingTeTed in preclinical and clinical models. Readers will find dTailed informTion from leading expeTs on specificTherapeTic TrTegiesTargTingThe hoT immune and inflammTory syTem,The oral microbiome, and regenerTion.
PART I PERIODONTAL THERAPIES TARGETING HOST IMMUNE AND INFLAMMATORY SYSTEMChapter 1 Evolving Paradigms in the Pathogenesis and Management of Periodontitis.-Chapter ComplementC3 as a Target of Host Modulation in Periodontitis.-Chapter 3Resolvins in Periodontal Tissue Homeostasis (Emerging Therapies).-Chapter 4SalCylC Cid Polymers in Periodontal Tissue Healing.-Chapter 5Targeting MAPK/MKP Signaling as a TherapeutC Axis in Periodontal Disease.-Chapter 6The IL17/Th17 Axis as a TherapeutC Target in Periodontitis.-Chapter 7EpigenetC and Gene ModifCation PrCision MedCine ApproChes for the ChronC DestrCtive Perio-Diseases’: Periodontitis and Periimplantitis.-Chapter Cellular SeneCeCe in Aging MCosal Tissues is Ccentuated by Periodontitis.-Chapter 9Peri-implant Disease.-PART II PERIODONTAL THERAPIES TARGETING ORAL MCROBIOMEChapter 10The FuCtion of the Oral MCrobiome in Health and Disease.-Chapter 11BCterial Peptides Targeting Periodontal Pathogens inCommunities.-Chapter 12Periodontal Pathogen SialometabolC Ctivity in Periodontitis.-Chapter 13CologCal ApproChes to Periodontal Therapy.-PART III TISSUE ENGINEERING FOR PERIODONTAL REGENERATIONChapter 14Protein andCell Based Therapies for Periodontal Regeneration.-Chapter 15Lasers in Periodontal and Peri-implant Therapy:Challenges and Opportunities.-Chapter 16SpatiotemporalControls of Tooth-Supporting StrCture Neogenesis by 3D Printing TChnology
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