图书简介
Hansen’s disease (leprosy) is endemic in more than 100 countries worldwide, with over 200,000 new diagnoses each year and more than 4 million people living with some form of HD-related impairment. The World Health Organization’s ‘Global Leprosy Strategy’ timeline for Hansen’s disease elimination indicates that it will be encountered in clinical practice in endemic countries for at least another decade. Increasing north-to-south migration, global travel and overseas medical work mean that physicians in non-endemic countries will also encounter patients with Hansen’s disease, which can affect people for many years before diagnosis and after treatment. For busy clinicians, it represents a challenge, in terms of disease learning and updating knowledge and skills.This book provides a concise, up-to-date, and comprehensive source of information on Hansen’s disease clinical practice. It covers essential topics on all clinical aspects, complemented by history, epidemiology, paleopathology, and the social impact of the disease. Edited and written by contributors with decades of experience, it’s divided into twenty-six chapters clarifying the genetics and neurological manifestations, physical disabilities and its prevention; oral, ophthalmological, and bone changes, among others.For the primary audience of practicing physicians, it is an affordable point of reference, whilst also being suitable for student and trainee doctors. It’s also accessible to general practitioners and specialists in dermatology, neurology, pediatrics, infectious disease, family and community medicine, and orthopedics, as well as to non-specialists and other healthcare professionals.
Chapter 1: Introduction to Hansen’s disease.- Chapter 2: The journey to a scientific understanding of leprosy: a brief outline.- Chapter 3: The origin, evolution and history of leprosy through a paleopathological lens.- Chapter 4: Hansen’s disease and Human Rights.- Chapter 5: Leprosy agents and principal methods of detection, identification and characterization of the leprosy agents.- Chapter 6: Epidemiology of Hansen’s Disease.- Chapter 7: Hansen’s Disease and One Health.- Chapter 8: Metabolic, genetic and immunological mechanisms in susceptibility to leprosy.- Chapter 9: Clinical aspects and classification of Hansen’s disease.- Chapter 10: Reaction in Hansen’s disease.- Chapter 11: Hansen’s disease in children.- Chapter 12: Neuropathophysiology in Hansen’s disease: mechanisms of nerve injury.- Chapter 13: Neurological manifestations.- Chapter 14: Evaluation, monitoring, and prevention of disabilities in Hansen’s disease.- Chapter 15: Ophthalmological alterations in Hansen’s disease.- Chapter 16: Ear, nose, throat and mouth alterations in Hansen’s disease.- Chapter 17: Osteoarticular alterations in Hansen’s disease.- Chapter 18: Diagnostic Imaging in Hansen’s Disease: Conventional Radiography, Computed Tomography, Magnetic Resonance Imaging, and Dual-energy X-ray Absorptiometry.- Chapter 19: Coinfection and immunosuppression in Hansen’s disease.- Chapter 20: Differential diagnosis of cutaneous lesions of Hansen’s disease.- Chapter 21: Differential diagnoses of the neurological manifestations of Hansen’s disease.- Chapter 22: Immune and Chemoprophylaxis in Hansen’s disease.- Chapter 23: Psychosocial aspects of Hansen’s diseases.- Chapter 24: Peripheral Nerve by Ultrasound in Hansen’s Disease.- Chapter 25: Electroneuromyography in Hansen’s Disease.- Chapter 26: Treatment of Hansen’s disease.
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