Molecular Biomarkers for Cancer Diagnosis and Therapy

Molecular Biomarkers for Cancer Diagnosis and Therapy

癌症诊断与治疗的分子生物标志物
肿瘤学

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作者

Ranbir Chander Sobti Haruhiko Sugimura Aastha Sobti

出版社

Springer Berlin Heidelberg

出版时间

2023年09月09日

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ＩＳＢＮ

9789819937455

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页码

738

语种

英文

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This book presents recent advancements, challenges, and clinical implications of molecular biomarkers in various cancers. This book highlights the clinical applications of biomarkers are extensive for cancer risk assessment, screening and early detection of cancer, accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring response. It also explores the progress of predictive biomarkers as an adjunctive tool to tumor immunotherapy in effectively identifying the efficacy of immune checkpoint inhibitors and discusses their future directions in achieving precision immuno-oncology. Further, the book examines the combination of next-generation sequencing and advanced computational data analysis approaches in the understanding of the genomic underpinnings of cancer development and progression. Towards the end, the chapter discusses the role of some commonly investigated phytochemicals and their epigenetic targets that are of particular interest in cancer prevention and cancer therapy. It is a must for researchers as well as advanced students and physicians in the field of cancer and clinical oncologists.

Chapter 1. Molecular Biomarkers of Cancer and their Diagnostic Applications.- Chapter 2. Statistical Models in Cancer Management.- Chapter 3. Deep Learning Techniques for Computer Aided Diagnosis of Various Cancers.- Chapter 4. Machine Learning Techniques in Computer Aided Diagnosis for Effective Detection of Malignant Tissues.- Chapter 5. Molecular Mechanisms of Oncogenesis.- Chapter 6. Application of CRISPR in Cancer Research and Treatment.- Chapter 7. Nanobiosensing Platforms for Early Detection of Cancer.- Chapter 8. Bionanotechnological Strategies and Tools for Cancer Prediction, Prevention and Therapy.- Chapter 9. Central Nervous System Tumors.- Chapter 10. Biomedical Approaches in the Research and Management of Head and Neck Squamous Cell Carcinoma.- Chapter 11. Applications of Molecular Biology and Biomedical Advances in Ocular Oncology.- Chapter 12. Molecular Markers in Oral Cancer.- Chapter 13. MicroRNAs as Tools for Early Diagnosis and Predicting Response to Therapy in Oesophageal Cancer.- Chapter 14. The Role of Complement Regulatory Proteins during Liver Homeostasis and Hepatitis C Virus-related Liver Disease.- Chapter 15. Metabolite based Biosignature of Pancreatic Cancer.- Chapter 16. Molecular Pathogenesis of Lung Cancer: Evolving Landscape based on Past Experience.- Chapter 17. Molecular Insights and Risk Factors Associated with Small and Non-Small Cell Lung Cancer.- Chapter 18. Deciphering the Role of Immune-Checkpoint Inhibitors in Lung Cancer Treatment.- Chapter 19. Bone Tumors: An Overview.- Chapter 20. Genomics in the ‘Personalize’ Management of Breast Cancer.- Chapter 21. Colorectal Cancer and Role of Biomarkers in Diagnosis, Prognostification and Personalized Treatment.- Chapter 22. Biomarkers in Renal Cell Carcinoma.- Chapter 23. Androgen and Estrogen Signalling Pathways in Prostate Hyperplastic Tissues: Opportunities for Therapeutic Targeting from Multiple Angles.- Chapter 24. Role of Circadian Rhythm in Hormonal Cancers.- Chapter 25. Recent Immunotherapeutic Approaches for Cancer Treatment.- Chapter 26. Importance of Adme for Anticancer Prodrugs.- Chapter 27. Personalized Medicine in Clinical Management of Breast Cancer - Where Do We Stand?.- Chapter 28. PABPC1: A Novel Emerging Target for Cancer Prognostics and Anti-Cancer Therapeutics.- Chapter 29. Recent Update on Pyridoxine Derivatives as Anticancer Agents with Overview on its Patents.- Chapter 30. Recent Advances in Iron Oxide Nanoparticles-based Nano Medicine for Prostate Cancer: A Review.- Chapter 31. Therapeutic Applications of Snake Venom Proteins as Anti-Cancer Agents.- Chapter 32. Revamping Anticancer Strategies by Modulating Tumor Microenvironment using Botanicals.- Chapter 33. Modulation of Epigenetic Regulators for Cancer Prevention by Dietary Phytochemicals: Tools for Personalized Nutrition.

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