Genomics Data Analysis

基因组学数据分析:错误发现率与经验贝叶斯方法

概率论

售   价:
186.00
发货周期:国外库房发货,通常付款后3-5周到货!
作      者
出  版 社
出版时间
2023年01月09日
装      帧
平装
ISBN
9781032475288
复制
页      码
140
开      本
216 x 138 mm (5.5 x 8.5)
语      种
英文
综合评分
暂无评分
我 要 买
- +
库存 50 本
  • 图书详情
  • 目次
  • 买家须知
  • 书评(0)
  • 权威书评(0)
图书简介
Statisticians have met the need to test hundreds or thousands of genomics hypotheses simultaneously with novel empirical Bayes methods that combine advantages of traditional Bayesian and frequentist statistics. Techniques for estimating the local false discovery rate assign probabilities of differential gene expression, genetic association, etc. without requiring subjective prior distributions. This book brings these methods to scientists while keeping the mathematics at an elementary level. Readers will learn the fundamental concepts behind local false discovery rates, preparing them to analyze their own genomics data and to critically evaluate published genomics research.Key Features:* dice games and exercises, including one using interactive software, for teaching the concepts in the classroom* examples focusing on gene expression and on genetic association data and briefly covering metabolomics data and proteomics data* gradual introduction to the mathematical equations needed* how to choose between different methods of multiple hypothesis testing* how to convert the output of genomics hypothesis testing software to estimates of local false discovery rates* guidance through the minefield of current criticisms of p values* material on non-Bayesian prior p values and posterior p values not previously published
本书暂无推荐
本书暂无推荐
看了又看
  • 上一个
  • 下一个