图书简介
Practical Pharmaceutics contains essential knowledge on the preparation, quality control, logistics, dispensing and use of medicines. It features chapters written by experienced pharmacists and scientists working in hospitals, academia and industry throughout Europe, including practical examples as well as information on current GMP and GMP-based guidelines and EU-legislation. In this second edition all chapters have been updated with numerous new as well as didactically revised illustrations and tables. A completely new chapter about therapeutic proteins and Advanced Therapy Medicinal Products was added.From prescription to production, from usage instructions to procurement and the impact of medicines on the environment, the book provides step-by-step coverage that will help a wide range of readers, students as well as professionals. It offers product knowledge for all pharmacists working directly with patients and it will enable them to make the required medicine available, to store medicines properly, to adapt medicines if necessary and to dispense medicines with the appropriate information for patients as well as caregivers about product care and how to maintain the quality of the product. The basic knowledge presented in the book will also be valuable for industrial pharmacists to remind and focus them on the application of the medicines manufactured.The basic and practical knowledge on the design, preparation and quality management of medicines can directly be applied by the pharmacists whose main duty is production in community and hospital pharmacies and in industry. Undergraduate as well as graduate pharmacy students will find knowledge presented in a coherent way and fully supported with relevant examples.Practical Pharmaceutics has become a reliable and recognised source for the acquisition of pharmaceutical-technological knowledge. The book is used in the curriculum of a number of international universities and schools of Pharmacy.
Chapter 1. Introduction (Paul Le Brun).- Chapter 2. Prescription Assessment (Andrew Loweya).- Chapter 3. Availability of medicines (Helena Jenzer).- Chapter 4. Product Design (Christien Oussoren).- Chapter 5. Biopharmaceutics (Henderik Frijlink).- Chapter 6.Physical Chemistry (Wouter Hinrichs).- Chapter 7. Raw Materials (Richard Lantink).- Chapter 8. Containers (Julian Smith).- Chapter 9. Microbiology (David Roesti).- Chapter 10. Impact on the environment (Bengt Mattson).- Chapter 11. Information Sources (Sin Ying Chuah).- Chapter 12. Oral solids (Boy van Basten).- Chapter 13. Oral Liquids (Antje Lein).- Chapter 14. Pulmonary (A.H. de Boer).- Chapter 15. Oropharynx (Craig Russell).- Chapter 16. Nose (Anita Hafner).- Chapter 17. Ear (Monja Gantumur).- Chapter 18. Eye (Jens Boventer).- Chapter 19. Rectal and Vaginal (Herman Woerdenbag).- Chapter 20. Dermal (Antje Lein).- Chapter 21. Parenterals (Marija Tubic-Grozdanis).- Chapter 22. Irrigations and Dialysis Solutions (Daan Touw).- Chapter 23. Radiopharmaceuticals (Rogier Lange).- Chapter 24. Therapeutic Proteins and ATMPs (Michel Eppink).- Chapter 25. Human Resources (Elfriede Nusser-Rothermundt).- Chapter 26. Occupational safety (Johannes Gerding).- Chapter 27. Premises (Farshid Sadeghipour).- Chapter 28. Equipment (Derk Allersma).- Chapter 29. Basic Operations (Herman Woerdenbag).- Chapter 30. Sterilisation Methods (Craig Russell).- Chapter 31. Aseptic Handling (Frits Boom).- Chapter 32. Production Quality Control and validation (Rogier Lange).- Chapter 33. Quality Requirements and Analysis (Mark Santillo).- Chapter 34. Stability (Daan Touw).- Chapter 35 Pharmaceutical Quality System (Reinout C.A. Schellekens).- Chapter 36. Risk management in pharmacy production (Elfriede Nusser Rothermundt).- Chapter 37. Documentation (Rik Wagenaar).-Chapter 38. Statistics (Pascal Odou).- Chapter 39. Logistics (Martin J. Hug).- Chapter 40. Product care and daily practice (Diana van Riet-Nales).
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