图书简介

D.J. Finney: David Williams; Part I: Review Papers; 1 Michael F.W. Festing: Are animal experiments in toxicological research the ’right’ size?; 2 David Salzburg: Estimating dose-response for toxic end-points; 3 Eryl Shirley: A literature review of statistical methods for the analysis of general toxicology datas; Part II: Overdispersion; 5 Kenneth J. Risko and Barry H. Margolin: Some observations on detecting extra-binomial variability within the beta-binomial model; 6 S,E, Paul and A. Islam: C(alpha) tests for homogeneity of proportions in toxicology in the presence of beta-binomial overdispersion; 7 David A. Williams: Overdispersion in logistic-linear models; Part III: LD50 Estimation; 8 Andrew P. Grieve: On likelihood and Bayesian methods for interval estimation of the LD50; 9 R.J. O’Hara Hines and W.G.S. Hines: The analysis of grouped longitudinal mortality data allowing for variable natural mortality; 10 A. Whitehead and R.N. Curnow: Statistical evaluation of the fixed-dose procedure; Part IV: General Applications; 11 Daniel Krewski, Yiliang Zhu and Karen Fung: Statistical analysis of overdispersed multinomial data from development toxicity studies; 12 Myrto Lefkopoulou, Andrea Rotnitzky and Louise Ryan: Trend tests for clustered data; 13 W. Urfer and M. Becka: Exploratory and model-based inference in toxicokinetics

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