Proteases in Health and Disease

图书简介

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases,爐his book will爃ighlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be爓ritten by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases will be discussed. The book highlights the roles of both intracellular and extracellular proteases in health and disease.

Part A: Molecular and Biochemical Aspects of Proteases.- 1. An Overview of Endoplasmic Reticulum Calpain System.- 2. Mitochondrial Calpains: Who, What, Where, When and Why?.- 3. Role of Calpains in Calmodulin Regulated Systems.- 4. Exercise and Matrix Metalloproteases: A Brief Overview.- 5. Regulation of Chondrocyte Matrix Metalloproteinase Gene Expression.- 6. Microbial Source of Fibrinolytic Protease and Its Biotechnological Potential.- 7. Aspartic Proteolytic Inhibitors Induce Cellular and Biochemical Alterations in Fungal Cells.- 8. Cysteine Proteases of Human Malaria Parasites.- 9. Proteases as Virulence Factors in Leishmania: Focus on Serine Proteases as Possible Therapeutic Targets.- 10. An Updated Inventory on Properties, Pathophysiology and Therapeutic Potential of Snake Venom Thrombin-like Proteases.- 11. Macrocyclic Protease Inhibitors Constrained into a ?-Strand Geometry.- Part B: Involvement of Proteases in Disease Processes.- 12. Regulation of MT1-MMP Activation and Its Relevance to Disease Processes.- 13. Role of Proteases During Intra-erythrocytic Developmental Cycle of Human Malaria Parasite Plasmodium falciparum.- 14. Proteases in Vibrio cholerae and Their Role in Pathogenesis.- 15. ADAMTS13: The von Willebrand Factor Cleaving Protease and Its Role in Thrombotic Thrombocytopenic Purpura.- 16. Role of Proteases and Their Tissue Inhibitors in Pregnancy Outcome.- 17. Matrix Metalloproteinases in Bone Health and Disease.- 18. Escalated Expression of Matrix Metalloproteinases in Osteoarthritis.- 19. Role of Proteases in Autism Spectrum Disorder.- 20. Role of Proteases in the Management of Hepatitis C Virus.- 21. Role of Protease in Inflammatory Lung Diseases.- 22. Involvement of Some Proteolytic Enzymes in Cardiac Dysfunction Due to Ischemia-Reperfusion Injury.

Trade Policy 买家须知

关于产品：
● 正版保障：本网站隶属于中国国际图书贸易集团公司，确保所有图书都是100%正版。
● 环保纸张：进口图书大多使用的都是环保轻型张，颜色偏黄，重量比较轻。
● 毛边版：即书翻页的地方，故意做成了参差不齐的样子，一般为精装版，更具收藏价值。
关于退换货：
由于预订产品的特殊性，采购订单正式发订后，买方不得无故取消全部或部分产品的订购。
由于进口图书的特殊性，发生以下情况的，请直接拒收货物，由快递返回：
● 外包装破损/发错货/少发货/图书外观破损/图书配件不全（例如：光盘等）
并请在工作日通过电话400-008-1110联系我们。
签收后，如发生以下情况，请在签收后的5个工作日内联系客服办理退换货：
● 缺页/错页/错印/脱线
关于发货时间：
一般情况下：
●【现货】下单后48小时内由北京（库房）发出快递。
●【预订】【预售】下单后国外发货，到货时间预计5-8周左右，店铺默认中通快递，如需顺丰快递邮费到付。
● 需要开具发票的客户，发货时间可能在上述基础上再延后1-2个工作日（紧急发票需求，请联系010-68433105/3213）；
● 如遇其他特殊原因，对发货时间有影响的，我们会第一时间在网站公告，敬请留意。
关于到货时间：
由于进口图书入境入库后，都是委托第三方快递发货，所以我们只能保证在规定时间内发出，但无法为您保证确切的到货时间。
● 主要城市一般2-4天
● 偏远地区一般4-7天
关于接听咨询电话的时间：
010-68433105/3213正常接听咨询电话的时间为：周一至周五上午8：30～下午5：00，周六、日及法定节假日休息，将无法接听来电，敬请谅解。
其它时间您也可以通过邮件联系我们：customer@readgo.cn,工作日会优先处理。
关于快递：
● 已付款订单：主要由中通、宅急送负责派送，订单进度查询请拨打010-68433105/3213。

Proteases in Health and Disease（Advances in Biochemistry in Health and Disease） 生物化学

Proteases in Health and Disease（Advances in Biochemistry in Health and Disease）
生物化学