G-Quadruplex DNA:Methods and Protocols(Methods in Molecular Biology)

G-四联体DNA:方法与规程(丛书)

遗传学

售   价:
1326.00
发货周期:预计8-10周发货
作      者
出  版 社
出版时间
2009年12月18日
装      帧
精装
ISBN
9781588299505
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页      码
276
语      种
英文
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库存 49 本
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图书简介
Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In ’G-Quadruplex DNA: Methods and Protocols’, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, ’G-Quadruplex DNA: Methods and Protocols ’promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA.
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