Long-non Coding RNA / The dark side of the genome

长链非编码RNA/基因组的黑暗面

分子生物学

售   价:
1230.00
发货周期:预计4-6周发货
作      者
出  版 社
出版时间
2018年01月01日
装      帧
精装
ISBN
9781785482656
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页      码
150
语      种
英文
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图书简介
The dark side of the genome represents vast domains of the genome that are not encoding for proteins - the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms.
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