Analyzing Biomolecular Interactions by Mass Spectrometry

通过质谱分析法的生物分子相互作用

制药工程

售   价:
1516.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2015年02月11日
装      帧
精装
ISBN
9783527334643
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页      码
400
语      种
英文
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图书简介
The study of biological affinity interactions gained substantial interest within the last years. Screening of such interactions is a hot topic in academia (e.g. characterization of protein complexes and protein-biomolecule interplay), as well as in industry and clinical applications, for example metabolite screening. In all of these techniques, mass spectrometry plays a central role. This monograph gives a complete overview of all relevant techniques for interaction studies and shows the scope and limitation of each method by numerous examples. Arranged in three distinct parts and written by international experts, the reader will become acquainted with more traditional approaches such as Effect Directed Analysis, as well as latest on-line screening systems integrating separation sciences, mass spectrometry, and biochemical assays. For the study of biological protein interactions, all relevant mass spectrometric approaches including native and ion mobility MS, chemical proteomics and interactomics are discussed in detail. Also the coupling of biosensor techniques such as SPR and microarray technologies for high throughput screening with mass spectrometry are presented, turning this book to a first choice for everybody interested in or working in the field of interactomics.
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