The Cytokine Network and Immune Functions

图书简介

Cytokines are well characterized molecules that control the communication between cells. Their importance in immunology is very critical for the control of the quantity and of the quality of each specific response against foreign antigens (virus, bacteria, ...). When the cytokine network is mis-regulated disease can appear (autoimmunity, immunodeficiencies like in AIDS or cancer). This comprehensive treatment of this exciting area of molecular medicine presents an informative description of the major cytokines together with coverage of their role in the different parts of the immune system and of their implication in immunopathology, and will be of great interest to medical researchers and academics in the field. Industrial researchers with an interest in immunology will also find this book useful.

Foreword; Overview: General aspects of cytokine properties and functions; CYTOKINES AND THEIR RECEPTORS: MOLECULAR ASPECTS; I - Interleukins 2, 4, 7, 9, 13 and 15; II - The Interleukin 6 family of cytokines and their receptors; III - Interleukin 10; IV - The Tumor necrosis factor (TNF) family and related molecules; V- The Interleukin 1 system; VI - Interleukin 12; VII - Transforming growth factor; VIII - The interferons: biochemistry and biology; IX - Chemokines; X - Cytokines and haematopoeisis; XI - Interleukins 16, 17 and 18; XII - Mechanisms of signal transduction; XIII - Regulation of lymphokinegene expression; CYTOKINES AND IMMUNE FUNCTIONS; XIV - Cytokines in the development of lymphocytes; XV - Cytokines in the functions of dendritic cells, monocytes, macrophages and fibroblasts; XVI - Cytokines in T-cell responses; XVII - Regulation of humoral immunity by cytokines; XVIII - Cytokines and the cellular mechanism of inflammation; XIX - Cytokines in the brain; XX - Deregulated immune responses in cytokine and cytokine receptor transgenic and knockout mice; CYTOKINES IN PATHOLOGY; XXIII - Cytokines and chemokines in acquired immunodeficiencies; XXIV - Allergic responses and cytokines; XXV - Cytokines in organ transplantation; XXVI - Cytokines and autoimmunity; XXVII - Cytokine antagonists and autoimmunity; XXVIII - Cytokines in cancer; XXIX - Immunotherapy, gene therapy, cytokines and cancer

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The Cytokine Network and Immune Functions 人体免疫学

The Cytokine Network and Immune Functions
人体免疫学